Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the remedy of several myeloma. Its synthesis or study is crucial for making sure the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-one): A essential compound inside the synthesis of imatinib, a drug that targets specific types of most cancers, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their analyze is crucial for optimizing the manufacturing process and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4 use of to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast most cancers. Various intermediates help in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and tiny mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is associated with the synthesis of adamantane derivatives, which have several purposes, including FULVESTRANT INTERMEDIATES--4(N-4) antiviral Qualities.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be Utilized in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication utilised to handle variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).